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An interesting preclinical study explored the activity of PIO, metformin (MET) and dapagliflozin (DAPA) individually and in combinations vs

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Songs research on non-small cell lung cancer (NSCLC) found that there is ferroptosis in cancer cells treated with cisplatin, and ferroptosis-resistant cancer cells could secrete miR-4443 through exosomes, which increase the expression of FSP1 in ferroptosis-sensitive cancer cells, thereby enhancing the resistance of the cancer cells to ferroptosis [29]