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A deficiency of B12 can lead to anemia and neurological abnormalities, but supplementation is a safe and cost-effective method of improving quality of life even when vitamin B12 levels are unknown
If twice daily, then administer once in the early morning, two hours prior to breakfast, and once in the evening, two hours following the subjects meal
Funding This research was supported by Consorcio Centro de Investigacin Biomdica en Red CIBER- de Diabetes y Enfermedades Metablicas Asociadas (CIBERDEM) (group [CB15/00071], leading group) and CIBER de Enfermedades Cardiovasculares (CIVERCV) [CB16/11/00257], Ministerio de Ciencia e Innovacin Instituto de Salud Carlos III (ISCIII), Spain
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