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Any changes to CPAP treatment should only be made following review by a sleep specialist and, where appropriate, a repeat sleep study

Their work further identified the switch defective/sucrose nonfermentable (Swi/Snf) chromatin remodeling complex as a key regulator of RORt-mediated histone modifications, revealing that Swi/Snf and RORt cooperate to orchestrate the epigenetic activation of Th17 differentiation genes

Pharmacol Res (2016) 113(Pt A):24556.10.1016/j.phrs.2016.08.034 151 EsbenshadeTABrowmanKEBitnerRSStrakhovaMCowartMDBrioniJD

And for decades, neuroscience offered precious few tools to intervene once this cascade began