can you take hrt with glp 1 GLP-1 + HRT: Why This Combo is Changing Menopause Weight Loss Weight-loss injections such as GLP-1

Because retatrutide includes GLP-1 agonism (which semaglutide was providing) plus GIP and glucagon agonism, the transition should not result in loss of appetite suppression during the switch

All of those things are there

L-cell differentiation is induced by bile acids through GPBAR1 and Paracrine GLP-1 and serotonin signaling

The etiology of depression remains unclear to date, and there are various hypotheses regarding the pathogenesis of depression in clinical practice, including the monoamine neurotransmitter hypothesis, the hypothalamicpituitaryadrenal (HPA) axis dysregulation hypothesis, the inflammatory cytokine hypothesis, and the neurotrophic factor hypothesis