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However, in a similar study performed to evaluate the effects of pyruvate with increased frequency of dosing (500 mg/kg i.p., 6 days a week) in SOD1 G93A mice, pyruvate was not able to alter the onset of the disease or survival of mice (Esposito et al., Lactate Lactate is the end product of the glycolytic pathway (Rogatzki et al., 2015) and also can be utilized as an energy fuel following its conversion into pyruvate and subsequent oxidation in the mitochondria (Schurr, 2008)

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DNA synthesis is essential for these processes, as it provides the genetic material necessary for cell division and differentiation

Maintain your timing separation to optimize bioavailability, but injection site proximity to target tissue significantly improves local effect