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It does not establish safety, clinical benefit, or an approved therapeutic combination

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Por un lado, CJC-1295 sin DAC se une al receptor de GHRH (GHRHR), una protena acoplada a protena Gs que, al activarse, incrementa la adenilato ciclasa, eleva el AMP cclico intracelular y favorece la sntesis y liberacin de hormona de crecimiento, adems de estimular la transcripcin del gen de GH

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