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Surgeons should consider how the timing of elective procedures might shift if GLP-1 therapy is inducing substantial weight loss or anatomical change, which is relevant for bariatric, abdominal or head and neck surgeries

Recently, an exendin 4-based GLP-1 receptor agonist with a long duration of action, allowing once-weekly administration, has been developed

Among the overweight, a 10% reduction in body weight lowers lifetime medical costs by nearly 35%, while going from obese to overweight can result in halving the costs over a lifetime

Healthcare providers may also recommend starting with a lower dosage and titrating to minimize side effects