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People with a prior history of gastrointestinal problems and aged individuals are more likely to suffer from intense stomach cramps and severe diarrhoea after taking high doses of vitamin B. Most people are able to get enough vitamin B12 from their diets, however, occasionally when running low, supplements or B12 injections may be recommended

GSH repletion has been proposed as a therapeutic intervention

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These study results show that vitamin E, following oral supplementation, not only serves as an adjunct therapy to promote symptoms of periodontal diseases but also possibly plays a vital role in keeping periodontal health