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Freeze-thaw cycling matters more for an amylin analogue than for a typical short peptide, since the phase transitions and concentration changes involved are recognised nucleation triggers for amyloidogenic sequences, so aliquot rather than repeatedly accessing a single stock
Unlike full-length human growth hormone, none of them seem to have any effect on blood sugar levels, insulin sensitivity or other hormonal pathways, this lessens the risk of major metabolic side effects
We are grateful to WH and KW for technical assistance with data collection
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