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Discussion Our study demonstrates distinct effects of IF-P on gut symptomatology and microbiome, as well as circulating metabolites compared to continuous CR

This is manifested by insufficient infiltration of antigen-presenting cells (APCs), which results in the failure to effectively capture DAMPs (e.g., ATP, HMGB1) released by dying tumor cells, thereby inhibiting cross-presentation of antigens and activation of cytotoxic T lymphocytes (CTLs) (82)

4.5 Zingiber officinale Zingiber officinale , commonly known as ginger, is a perennial, herbaceous plant belonging to the Zingiberaceae family