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A recent clinical trial in type 2 diabetes patients with CVDs following captopril treatment (12.5 mg/day, P.O for 3 months) found a significant improvement in plasma GSH levels and a concomitant decline in lipid peroxidation [241]

doi: 10.1016/j.molmet.2020.101102 59 UccellatoreAGenoveseSDicembriniIMannucciECerielloA

Evidence from animal studies, nonhuman primate work, and limited early human data suggests that these medications may reduce alcohol consumption, drug cravings, relapse behaviors, and dopamine-driven reward responses

For example, semaglutide, liraglutide and tirzepatide are more often linked with constipation, while semaglutide stands out for its association with increased GERD symptoms