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In LEADER, there was a higher, albeit non-significant, rate of adverse retinal events with liraglutide compared with placebo (HR 1.15, 95% CI 0.871.52
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The pretreatment with Ab reduced the systemic levels of inflammatory cytokines (TNF-, IL-1), increased the antioxidant response in several organs and tissues (GSH and TEAC) with concomitant inhibition of oxidative damage (lipid peroxidation in serum, peritoneal cavity, heart and liver) of septic mice
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