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Nowell J, Blunt E, Edison P (2023a) Incretin and insulin signaling as novel therapeutic targets for Alzheimers and Parkinsons disease

Under conditions of hypoxia, nutrient deprivation, or impaired mitochondrial function, cancer cells modulate NADPH and GSH levels through key metabolic pathways such as the pentose phosphate pathway (PPP), FAO, and glutamine metabolism, thereby establishing a metabolicredox feedback loop [39,40,41]