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Another recently discovered mechanism by which proteins and particulates and possibly bacteria can penetrate the mucosa is via GAPs, in which large solutes such as 10 kDa dextran and proteins such as albumin traverse the mucosa where they are presented to subepithelial dendritic cells [19, 53, 62]

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In our study, a marked accumulation of the colocalization of bound/free GTP with small GTPases Arl8b and Rab7 in both genotypes suggests a lack of endolysosomal mobilization in old age neurons

1 2 "Exendin-4 induced glucagon-like peptide-1 receptor activation reverses behavioral impairments of mild traumatic brain injury in mice"