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It was first isolated and characterised by Professor Predrag Sikiric and his research group at the University of Zagreb in the early 1990s, with the foundational paper published in the Journal of Physiology (Paris) in 1993

PKC) (PI3K-Akt) signaling, and NF-B signaling, to name a few [97]

Key characteristics: Normal inhabitant: Candida naturally lives in the gut, mouth, and vagina in most people Sugar-dependent: Candida uses sugars as its primary energy source and is an efficient fermenter Polymorphic: It can exist in multiple formsas rounded yeast cells or as invasive branching filaments (hyphae) that can penetrate tissues Biofilm-forming: Candida can create protective biofilm communities with other microbes, making it difficult to eradicate The most common species affecting humans is Candida albicans , though others like C

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