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doi:10.1111/dom.13358 187

Leucine in particular is a potent insulin secretagogue

Amylin receptors are heterodimers of the calcitonin receptor (CTR) with receptor activity-modifying proteins, giving AMY1, AMY2 and AMY3, and cagrilintide activates these alongside CTR itself, which is why the literature classifies it as a dual amylin and calcitonin receptor agonist rather than a selective amylin analogue