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The participants were divided into five treatment groups: bofanglutide 12 mg (biweekly) bofanglutide 18 mg (biweekly) bofanglutide 24mg (biweekly) bofanglutide 24mg (once weekly) semaglutide 1mg (once weekly) The primary measurement the researchers focused on was HbA1c levels from the baseline to the 24-week follow-up

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2023;42:e111901

Regarding thyroid effects: rodent studies with related GLP-1 receptor agonists have shown C-cell changes, but no causal link to thyroid tumours in humans has been established in UK or EU regulatory assessments