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The approval marks the fourth NSCLC indication for Tagrisso, which is also authorized for the first-line treatment of metastatic disease, as an adjuvant therapy after resection and in metastatic NSCLC that has progressed after EGFR tyrosine kinase inhibitor (TKI) treatment
Understanding these genetic predispositions may help contextualize why some individuals struggle with sustained weight loss despite behavioral interventions, and why GLP-1 therapywhich directly activates GLP-1 receptorsmay be especially relevant for certain genetic profiles
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