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Potential Metabolic Rate Enhancement: Through activation of beta-3 adrenergic receptors and thermogenic effects, AOD-9604 may increase resting energy expenditure

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Indeed, in pre-clinical models, retatrutide, a triple agonist (GLP-1/GIP/glucagon), resulted in greater WL and improved glucose profile compared to tirzepatide through increased energy expenditure and reduced calorie intake [80, 81]

It enhances feelings of fullness and reduces hunger, helping individuals consume fewer calories