Peptide therapy is usually gradual, so the first signs may be subtle before they become measurable
To overcome these issues, we applied a Standard Addition Method (SAM) 52 to mouse liver samples, in which the tissue samples were derivatised with IAM-TPP to trap any GSS as GSS-CAM-TPP, while also being spiked with a concentration range of GSS-CAM-TPP followed by quantification of total GSS-CAM-TPP
The peptides ability to cross the blood-brain barrier and affect central nervous system tissue remains partially characterized but has generated interest in neurological applications
Next, to examine whether hydrogen is actually generated in the intestinal tract (especially in the large intestine) of mice administered the Si-based agent, the levels of hydrogen in the stomach, small intestine, cecum, colon, and rectum were analyzed with gas chromatography