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The diluent is directed slowly against the inside wall of the vial rather than sprayed onto the powder, and the vial is gently swirled rather than shaken, because vigorous agitation can shear peptide bonds and denature the material

[DOI] [PMC free article] [PubMed] [Google Scholar] 28.Gojkovic S., Krezic I., Vranes H., Zizek H., Drmic D., Batelja Vuletic L., Milavic M., Sikiric S., Stilinovic I., Simeon P., et al

Herrera-Gomez F, Asensio-Gonzalez M, Gonzalez-Lopez A, Alvarez FJ

This is the same mechanism behind PT-141 (bremelanotide), which is an FDA-approved derivative of MT-II specifically designed for sexual dysfunction