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In the FINE-HEART pooled analysis of these three large clinical trials, finerenone also reduced the risks of HHF, composite kidney outcome without macroalbuminuria, MACE, and all cause death [55]

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In this study, dose-escalation of LY3437943 to 12 mg once weekly over a period of 12 weeks resulted in an additional body-weight loss of 9 kg compared with both the placebo and dulaglutide, while demonstrating an acceptable safety profile