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Although this could potentially have adverse cardiac effects, GLP-1 receptor agonists have been shown to protect cardiac myocytes against ischaemia in animal and human studies

Data across multiple trials consistently shows that dual agonists (GLP-1 plus GIP) produce lower nausea rates than GLP-1-only compounds

It works in the brain to suppress appetite, in the gut to slow digestion, and across multiple organ systems to shift how your body processes energy

Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study Nature Medicine 2019;25(7):1096-1103 doi:10.1038/s41591-019-0495-2 (Human trial, small) Suenaert P, Segers A, Rymenans L, et al