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Participants also recorded reductions in waist circumference (average 7.1cm loss on 6mg, 8.2cm on 12mg, 10cm on 36mg, compared with 3.1cm loss on placebo), blood pressure (estimated -4.2 and -1mm HG difference between placebo and orforglipron in systolic and diatolic blood pressure, respectively) and cholesterol (-2.1% difference between placebo and orforglipron)
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L-Arginine: Does It Lower Blood Pressure
In addition to direct health issues, MASH is linked to metabolic syndrome -- a group of conditions including high blood pressure, high blood sugar, excess belly fat and unhealthy cholesterol levels
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