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In rodent studies, it has reduced neuronal damage from hippocampal ischemia-reperfusion injuries and reduced the effects of traumatic brain injury lesions

They are usually induced by corticosteroids, anti-tubercular drugs, anticonvulsivants, antipsychotics and some anti-cancer agents [1]

T cells from children with ASD had a different pattern of co-stimulatory and activation markers following in vitro stimulation, with significantly increased expression of CD137 (4-1BB) but lower expression of CD134 (OX40) and CD25 (IL-2 receptor) [111]

You can think of it like a savings account for iron there when your body needs it for things like making red blood cells, supporting your brain, and carrying oxygen to your muscles