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[7] Administration therefore restores physiologic androgen levels, suppresses hypothalamic gonadotropin-releasing hormone and pituitary luteinizing hormone, stabilizes nitrogen balance, increases lean body mass and may improve mood and sexual function, yet prolonged suppression of intratesticular testosterone can reduce spermatogenesis, underscoring the need for careful dose titration and fertility counseling when indicated

Target Engagement Unlike many regulatory peptides that function through a single well defined receptor, BPC-157 appears to interact with multiple molecular components involved in vascular and connective tissue signaling

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