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These results underscore the pivotal involvement of VSMC ferroptosis in the development of AA and indicated that targeting ferroptosis could effectively mitigate pathological vascular remodeling, providing a promising therapeutic approach for AA prevention

controls Rabbit wounds: GHK alone or combined with helium-neon laser improved wound contraction, boosted granulation tissue, increased antioxidant enzyme activity, and stimulated new blood vessel growth Diabetic rat models: PIC dressings with GHK showed higher glutathione and ascorbic acid levels, better epithelialization, and stronger fibroblast activation New Blood Vessel Formation Wounds cant heal without blood supply

Commun Med (Lond) 1

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