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At the same time, these vessels function as conduits that facilitate continual infiltration of immune cells and inflammatory mediators, creating a self-reinforcing cycle of inflammation and angiogenesis

3.4.1 Protective effects of metformin on cardiovascular disease risk in patients with polycystic ovary syndrome Epidemiological research suggests that individuals with PCOS exhibit a greater prevalence of hypertension compared to those without PCOS, particularly among females of reproductive age, and their cardiovascular risk is notably elevated irrespective of their BMI