fatigue while taking semaglutide Fatigue: Does Semaglutide Make You Tired? Why Semaglutide Makes You Tired:

For patients with severe renal insufficiency (CrCl less than 30 mL/min, approximately corresponding to serum creatinine levels of greater than 3.0 mg/dL in men and greater than 2.5 mg/dL in women) or with end-stage renal disease (ESRD) requiring hemodialysis or peritoneal dialysis, the dose of Januvia is 25 mg once daily

Supplementing isn't a one-time event

When she was as young as five years old, her doctors started trying to figure out why

This suggests the eventual prescribing approach may involve reaching a target weight and then adjusting the dose downward to maintain it, rather than stopping treatment entirely