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Testing guides our treatment

Behav Brain Res 2011;221:564-73

Effects of Liraglutide on clinical stability among patients with advanced heart failure and reduced ejection fraction: a randomized clinical trial

As SeniorSite synthesized in its July 2026 review of the current evidence: older adults should have a baseline DEXA scan to establish bone and lean mass before starting, a protein target of at least 1.2 to 1.6 grams per kilogram of body weight per day (substantially higher than the standard 0.8g/kg guidance), resistance training incorporated as a non-optional companion to drug therapy, and a slower dose escalation than standard protocols to reduce the rate of weight loss and minimize lean mass sacrifice