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Ethanol has been shown to downregulate the expression and/or impair the function of excitatory amino acid transporters (EAAT1/GLAST and EAAT2/GLT-1), leading to extracellular glutamate accumulation, loss of synaptic compartmentalisation and increased excitotoxic stress on neighbouring neurons [20,64,65,66,67,68,69]
Moreover, elevated GDF8 levels in women with PCOS often function as a predictor of poorer pregnancy outcomes when women are undergoing IVF treatment (290)
5 The presence of a delta wave (Figure 2 2 ) indicates an accessory pathway, 6 although accessory pathway conduction may be concealed
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