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In addition, longitudinal monitoring of circulating biomarkers and proteomic signatures could provide a means to assess therapeutic response at the molecular level, enabling more precise and personalized cardiovascular risk stratification

Consistent energy levels: While some people experience fatigue, others begin to feel more stable energy as blood sugar levels start to even out

Patients should promptly report any concerning symptoms to their healthcare providers, particularly severe or persistent muscle pain

In an announcement published on 21 May 2026, Eli Lilly shared the results of the TRIUMPH-1 study, which involved 2,339 participants who were randomised to receive either retatrutide 4mg, 9mg, 12mg (building up every four weeks from 2mg), or placebo