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In most human trials concerning UA, the doses that exhibit significant physiological effects are typically approximately 1,000 mg/d

Internal reference selection for special sample types Secreted samples such as plasma, breast milk, tissue fluids, etc.: Secreted proteins such as Transferrin can be selected as an internal reference due to the lack of intact cellular structure

However, the body's production of hyaluronic acid tends to decrease with age, which contributes to the appearance of the first signs of aging

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