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As endogenous GLP-1 has a very short half-life, these central actions are likely to be more relevant during therapeutic use of DPP4-resistant GLP-1R analogs, or in post-gastric bypass surgeries, in which GLP-1 equivalent levels, or postprandial GLP-1, respectively, are augmented and sufficient to elicit anorectic responses at these CNS targets

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117 In an rodent model of PCOS, the addition of cinnamon to androgen treatment blunted the changes in ovarian function and structure that occurred with androgen treatment alone

Kadonosono, T., Yamano, A., Goto, T., Tsubaki, T., Niibori, M., Kuchimaru, T., et al., J