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According to Masson staining of RV tissues in HPH rats, fibrosis levels were significantly higher in the hypoxia group than in the control group but were significantly decreased in the POH (25, 50, and 100 mg/kg/d) and sildenafil (30 mg/kg/d) groups (Fig

In the future, if its safety and efficacy are further verified, it may obtain drug approval, thereby promoting the expansion of the market size

These results agree with El-Rashidy and collaborators who reported that there was significant increase in the weight, z-score for weight, height, and z score for height with non-significant change in BMI and BMI z-score after KD treatment 22

Diarrhea affected 33% to 35% of participants