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Figure 5 Table 1 Pharmacological characteristics and advantages compared to Erastin for representative analogs/derivatives

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These medications are not recommended for people who are:PregnantHave a personal or family history of medullary thyroid cancerHave a condition called multiple endocrine neoplasia type 2Have had pancreatitis People with serious stomach conditions such as gastroparesis, those with advanced kidney disease and are prone to dehydration, and individuals with pre-existing diabetic eye disease should use these medications carefully and under close supervision by a healthcare provider.How GLP-1s compare to other treatments Compared with other medications for obesity and diabetes, GLP-1s deliver strong benefits