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TABLE 3 Cardioprotective and Therapeutic Effects of Metformin Across cardiac pathologies

Symptoms Daytime sleepiness or fatigue Difficulty falling or staying asleep Waking up too early or feeling unrefreshed Impaired concentration, memory, and performance Mood changes: irritability, depression, or anxiety Unusual behaviors during sleep: snoring, gasping, limb movements, sleepwalking, or teeth grinding126 Diagnosis Clinical history: Detailed patient and, if possible, bed partner or family reports4