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Description

Dodd et al, 2019)

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IL-24, an immunoregulatory cytokine belonging to the IL-10 family, signals through IL-20R1/IL-20R2 and IL-22R1/IL-20R2 heterodimeric receptors to activate the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway, primarily inducing STAT1 and STAT3 phosphrylation 15

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These findings highlight the multifaceted strategies by which TCM compounds compromise fungal membrane function, offering promising avenues for antifungal development, particularly against drug-resistant strains

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Kidney, however, showed a mild increase in phosphorylation in GK rats but significant activation was observed in control Wistar rats after exercise

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