Now, newer evidence suggests that GLP-1s may help with depression and anxiety, too
Key outcomes: Mean weight loss: 14.9% (vs 2.4% placebo) 86.4% of participants achieved 5% loss (vs 31.5% placebo) 50.5% achieved 15% loss (vs 4.9% placebo) SELECT (Lincoff et al., NEJM 2023) added the cardiovascular signature: in 17,604 non-diabetic adults with prior CV history, semaglutide 2.4 mg reduced MACE (CV death, MI, stroke) by 20% over 3 years
But one study conducted in the United Kingdom in 2024 with 204 people with Alzheimers disease found that liraglutide helped to slow down cognitive decline by 18 percent over the course of a year compared with those taking a placebo (Manalac, Dec 2024)
Different from normal melanocytes, which are regularly interspersed as single cells among basal keratinocytes, forming the so called epidermal-melanin unit, nevomelanocytes tend to cluster in compact so called theques (9)