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SEROQUEL potentiated the cognitive and motor effects of alcohol in a clinical trial in subjects with selected psychotic disorders, and alcoholic beverages should be limited while taking quetiapine

By inhibiting Aurora-A, Aurora-B, and Aurora-C kinases, these compounds induce defects in mitotic spindle assembly, causing temporary cell cycle arrest and disrupting proper chromosome alignment during mitosis [78]

In contrast, constipation can often be alleviated by increasing dietary fibre and fluid intake, with the possible use of stool softeners and encouragement of regular physical activity [15]