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The authors note the meta-analysis did not include studies of lifestyle interventions and bariatric surgery, reducing the degree to which different weight loss approaches could be compared within the context of the study

Beyond the physiological interactions, alcohol provides empty calories (7 calories per gram, almost as much as fat at 9 calories per gram) and impairs judgment about food choices

In addition, GLP-1 inhibits glucagon release (which slows down the release of sugar into the blood so that you burn more fat), slows down gastric emptying (makes you feel full), and lowers the desire for food intake (because you feel full)

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