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IBRO Neuroscience Reports

The GHK Tripeptide and Its Copper Complex The GHK sequence glycine, histidine, lysine is small enough to qualify as a "signal peptide," meaning it interacts with cell-surface and intracellular targets to alter transcriptional programs rather than acting as a structural building block

The finding established that the GSH redox cycle is the primary intracellular antioxidant defence system in endothelial cells against peroxide-mediated oxidative stress, and remains a foundational reference for endothelial oxidative stress research using GSH manipulation