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Notably, the STEP TEENS trial showed that semaglutide 2.4 mg, administered once weekly via subcutaneous injection, can be used in individuals aged 12 years and older, as adolescents with obesity treated with semaglutide experienced a significant reduction in BMI compared with placebo, along with improvements in several cardiometabolic risk factors [47]

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Market reports indicate that Novo Nordisks CagriSema (an injectable weight-loss drug), while effective, did not surpass the efficacy of Eli Lillys tirzepatide under the same administration method and duration