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How GLP-1 Medications Work for Weight Loss GLP-1 medications work by mimicking incretin hormones natural signals your gut releases after eating that tell your brain and pancreas how to respond

Both hormones have a very short half-life (the time corresponding to a loss of half of their physiological activity), of only 1-2 minutes, in particular due to their degradation by dipeptidyl peptidase-4 (DPP-4)

The following variables were included in a logistic regression model used to estimate propensity scores (PS): age, gender, pre-existing cardiovascular disease (coronary heart disease, stroke, transient ischemic attack, acute myocardial infarction, peripheral vascular disease) and heart failure

Studies suggest it might lower these male hormones