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4d is a highly promising novel inhibitor of GLS1 [184]
GLP-1s and Lean Mass: What the Research Shows Glucagon-like peptide-1 (GLP-1) receptor agonists have been making headlines for their dual role in managing type 2 diabetes and facilitating weight loss
The glutathione peptide of one inhibitor, termed productive binding, occupies the G-subsite with multiple interactions similar to those observed for other glutathione S-transferases, while the glutathione backbone of the second inhibitor, termed unproductive binding, exhibits only weak interactions mediated by two polar contacts
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