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Description

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Cagrilintide is an amylin analogue, not a GLP-1 receptor agonist, so it works through a distinct hormonal pathway

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This includes the downregulation of Bax (a pro-apoptotic marker), upregulation of Bcl-2 (an anti-apoptotic protein), and increased expression of proliferating cell nuclear antigen (PCNA), a key marker of cell proliferation [65]