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In the five in vitro studies, although a decrease in the apoptosis rate of granulosa cells was observed at specific doses, it was not confirmed whether this effect could translate into an improvement in oocyte quality in vivo (Fabov et al., 2023
Effects of folic acid on oligozoospermia with MTHFR polymorphisms in term of seminal parameters, DNA fragmentation, and live birth rate: a double-blind, randomized, placebo-controlled trial
Regular alcohol consumption during long-term nitrofurantoin prophylaxis compounds this risk by adding alcohols direct hepatic burden
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