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Description

The parameter was significantly reduced in GO (23%), GO + amlodipine (25%), GO + aminoguanidine (22%), and GO + NAC (15%) compared to BSA (Fig

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Biomarkers are grouped by biological function: inflammatory markers (TNF-, IL-1, IL-6, IL-12, IL-10, CRP), endothelial activation markers (ICAM-1, VCAM-1, MCP-1, P-selectin, L-selectin), oxidative stress markers (ROS, NOX4), antioxidant markers (NO, SOD), matrix remodeling markers (MMP-9), matrix remodeling endogenous inhibitors (TIMP-1), plasma biomarkers (OPG), and Cardiovascular risk markers (NT-proBNP, ANGPT2, THBS2, MSR1, and TNC)

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