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Their review argued that the original sequence determination was performed once and not re-verified by modern methods, and that endogenous DSIP-like immunoreactivity in mammalian tissue may reflect related peptides rather than the synthetic nonapeptide as drawn (Kovalzon & Strekalova, 2006)
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The copper chelator tetrathiomolybdate, which blocks the copper-dependent catalytic activity of LOX, is presently undergoing a phase II study (NCT00195091) involving patients with breast cancer at moderate to high risk of recurrence
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