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Description

The backstory: GLP-1s is a class of drugs that include semaglutide (Ozempic, Wegovy, Wegovy pill), tirzepatide (Mounjaro and Zepbound), and now orforglipron (Foundayo)

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Collectively, these mechanisms establish a connection between MASLD and diastolic dysfunction, arrhythmias, and a heightened risk of HFpEF [36]

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doi: 10.1177/089198879300600207 7 BessiV.MazzeoS.PadiglioniS.PicciniC.NacmiasB.SorbiS.et al

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Overall, this and smaller studies have reported differing and inconclusive results related to dysbiosis and IC/BPS, and more research is needed (

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